Articles

Dermatology in India

vendredi, mars 20th, 2015




Demographics and Economics India is a populous country with close to 1.3 billion individuals. But contrarily to China it is still growing. Nevertheless, the Gross Domestic Product (GDP) is only US5 trillion (United States US16 trillion) and only 3.9% of GDP expenditure is for healthcare (United States: 17.9%) Enough dermatologists ? In absolute terms there […]

Effet du finastéride dans la calvitie en fonction de l’age

lundi, décembre 1st, 2014




Global photographic assessment of men aged 18 to 60 years with male pattern hair loss receiving finasteride 1 mg or placebo. Olsen EA, Whiting DA, Savin R, Rodgers A, Johnson-Levonas AO, Round E, Rotonda J, Kaufman KD; Male Pattern Hair Loss Study Group. J Am Acad Dermatol. 2012 Sep;67(3):379-86. doi: 10.1016/j.jaad.2011.10.027. Epub 2012 Feb 9. […]

The Anti-Aging Effects of Hyaluronic Acid: Beyond Fillers

vendredi, octobre 10th, 2014




Age-related changes are due to many factors influencing the structure of the epidermis (texture changes) as well as changes in the dermis (loss of volume). The following study shows the role of hyaluronic acid (HA), BOTH large and small fragments in Epidermal age related skin changes. This study shows that topical application of small HA […]

Faster Wound Healing in Psoriasis and Why ?

vendredi, octobre 10th, 2014




Central to that is calcium regulation which allows changes in cellular differentiation. The N-methyl-D-aspartate receptor (NMDAR) is important for this and is abnormally expressed in psoriasis lesions. In this study, the speed of wound healing is suggested to be faster in psoriasis wounds as compared with wounds of unaffected individuals. Psoriasis shares many things in […]

Androgenetic Alopecia Treatment with Platelet Rich Plasma (PRP)

vendredi, octobre 3rd, 2014




Androgenetic alopecia is an often hereditary condition with thinning of the hair into vellus hairs which occurs in males and females according to a male pattern (Hamilton classification) or a female pattern (ludwig classification) It is psychologically devastating and treatments include topical (minoxidil), oral (finasteride) treatments sometimes so ineffective that the only solution is wearing […]

Fighting Skin Aging by Targeting the Degradation of Collagen by Collagenase

mardi, septembre 30th, 2014




Skin aging (ageing) concerns the skin, in the epidermis where it is responsible for texture changes. However the most visible effect of aging is loss of volume in the dermis. In the dermis intact collagen fibers (as well as hyaluronic acid) play an important structural role in its volume. The visible changes in aging are […]

Oral Fumaric Acid: how long is it tolerated ?

mardi, septembre 30th, 2014




Fumaric acid esters (FAE) (oral intake) are used in come countries (Germany…) in the treatment of psoriasis. It is an effective drug however its limitations lie in the fact that it can cause gastrointestinal symptoms as well as flushing In this retrospective study from Ireland done in 249 patients, demographic data, length of treatment, reasons […]

Photophoresis-induced Red Blood Cell Disorders

vendredi, août 22nd, 2014




Extracorporeal photophoresis (ECP) has been used for the treatment of cutaneous T cell lymphoma, including graft versus host disease (GVHD), solid organ transplant rejection, scleroderma, atopic dermatitis, epidermolysis bullosa acquisita, lichen planus, lupus erythematosus, pemphigus vulgaris, Crohn disease, and type 1 diabetes. This article is a casease report of a rare autoimmune hemolytic anemia called […]

Pemphigus Vulgaris: Defining Disease States And Treatment Outcomes

jeudi, août 21st, 2014




Pemphigus vulgaris is an autoimmune bullous skin disease which is divided into pemphigus vulgaris (disorder of desmoglein 3) and Pemphigus foliaceus (desmoglein 1, endemic form=fogo selvagem). This consensus has all its sense especially for pemphigus vulgaris as it is a non curable disease. Therefore it is very important to be able to classify disease states, […]

The Role of Infections in Lymphomas of the Skin

jeudi, août 21st, 2014




It is not exactly a secret that when things go wrong in lymphocytes, which are so important in immunosurveillance, there are consequences on the organism’s defense against external agents. Conversely, as this review shows, infectious agents might be able to regulate T lymphocytes. Soft cell tumors affect lymphonodes, but they can initially affect the skin […]

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