Pigmentation, Hyperpigmentation and Solutions
Menu Pigmentation, Hyperpigmentation and Solutions
Protected: “Traditional” Depigmenting Products – Table of Contents
Thursday, October 25th, 2012There is no excerpt because this is a protected post.
Protected: Pigmentation Disorders – Table of Contents
Thursday, October 4th, 2012There is no excerpt because this is a protected post.
Skin colour measurement
Wednesday, August 29th, 2012A few devices exist for the measurement of skin colour. These devices are generally called skin colorimeters. The most well-known existing colorimeters are Chromameter, Mexameter, and the newly developed device DermaCatch. Skin colorimeters are usually equipped with a handpiece which is put on the desired area of the skin and emits certain wavelenghts on the [...]
DERMACATCH – The latest advancement in skin colour measurement
Wednesday, August 29th, 2012Precise skin color (colour) measurement is of the utmost importance for researchers as well as clinicians involved in the field of skin pigmentation. Skin colorimetry has proved to be a delicate and rather complex issue. This complexity results from several facts: Skin erythema, which readily changes due to internal or external factors, can highly interfere [...]
Kojic acid
Wednesday, March 21st, 2012Kojic acid It is a fungal metanolite which inhibits the enzyme tyrosinase. It binds to copper which becomes unusable by melanocytes. It is used at a concentration of 1% Its therapeutical effets are weak to moderate. To learn more about a safe and effective depigmenting cream, click here. Bibliography: Katsambas A (Conflicts of interest: Abbott, [...]
Hydroquinone (HQ)
Wednesday, March 21st, 2012Hydroquinone (HQ) Mechanism of action: hydroquinone inhibits activated tyrosinase activity (therefore it does not act on normal skin). A word on available concentrations: 2%: often ineffective 3-5%: good bleaching agent 6-10%: higher concentrations can cause irritation Side effects: Contact dermatitis (Both Allergic and Irritant) Nail Discoloration Exogenous Ochrnosis can rarely occur in dark skin individuals [...]
L-ascorbic acid (Vitamin C)
Tuesday, March 20th, 2012L-ascorbic acid (Vitamin C) Is an antioxidant Is used in the treatment of disorders of pigmentation including melasma (chloasma) (pregnancy mask) Alters the color of melanin from jet black to light tan Unstable as quickly oxidized To learn more about a safe and effective depigmenting cream, click here. Bibliography: Katsambas A (Conflicts of Interest: Abbott, [...]
New Depigmenting substances
Monday, February 20th, 2012To learn more about a safe and effective depigmenting cream, click here. New Depigmenting substances: N-acetyl glucosamine Artocarpanone 4-n-butylresorcinol (rucinol) Ursolic Acid Anthraquinones Cinnamic Acid Macelignan Gallic Acid Glycine Isopanduratin A and 4-Hydroxypanduratin A Kurarinol, Kurarinidol and Trifolirhizin Pycnogenol 8% topical indomethacin cream Selina dien-8-one Taxifolin DeoxyArbutin and its second generation derivatives Hydroperoxy Traxastane t; [...]
Existing Depigmenting substances
Monday, February 20th, 2012They act through: Tyrosinase Inhibition Inhibitors of Inflammation-induced Melanogenic Response Peroxidase inhibition Product Reduction and ROS (Radical Oxygen Scavengers) Tyrosinase inhibition hydroquinone 4-hydroxyanisole 4-S-CAP and derivatives Arbutin Aloesin Azelaic Acid Kojic Acid Ellagic Acid Resveratrol Oxyeresveratrol Licorice Extract Lactic Acid Inhibitors of Inflammation Induced Melanogenic Response Chamomille Corticosteroids Gliabridin Tranexamic Acid Peroxidase [...]
Pigmentation by Melanin and Skin Color (Colour)
Tuesday, November 16th, 2010In humans, melanin pigments are responsible for the visible color of the skin, hair and eyes. Although the blood within the dermis and exogenous pigments as carotenoids may play a role in producing different skin hues, variations in skin pigmentation between different ethnic groups (namely Negroid, Asian and Caucasians) is primarily determined by the amount [...]
