Vancomycin-induced Neutrophilic Dermatosis
- Vancomycin is an antibiotic used for intravenous treatment of bacterial infections, particularly hospital (nosocomial) acquired ones such as with Methicillin Resistant Staphlococcus Aureus (MRSA) infections, which are resistant to penicillin.
- Vancomycin is known to create neutropenia but the following case report reports the occurrence of a neutrophilic dermatosis mimicking cryptococcus. No organism was found and this is therefore an aseptic skin condition of Sweet’s syndrome is part of.
- Neutrophilic dermatoses is poorly understood when it comes to knowing the cause but hopefully this case report could allow more understanding.
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Dr Christophe Hsu – dermatologist. Geneva, Switzerland
Source of information: Vancomycin-associated neutrophilic dermatitis histologically mimicking Cryptococcus. Boyd AS, Ortleb M. J Am Acad Dermatol. 2014 Apr;70(4):e86-8. doi: 10.1016/j.jaad.2013.11.025.