“Traditional” Depigmenting Products


Sunday, October 31st, 2010

Hydroquinone (HQ) is the most widely used skin depigmenting agent. This agent has a moderate skin depigmenting effect and acts by reducing the number of melanin synthesizing cells in the epidermis. Formulations containing up to 2% HQ are allowed by FDA to be used for skin whitening in normal individuals. These formulations can be purchased […]

Monobenzone 20% (Benoquin)

Saturday, October 30th, 2010

This product is known as Benoquin. Benoquin is a very potent skin whitener and may cause complete and permanent skin depigmentation. Benoquin must never be used on normal skin to produce a white complexion nor is it allowed to be utilized for the treatment of hyperpigmentary disorders as melasma, freckles, liver spots… The sole indication […]

Monobenzone 40%

Friday, October 29th, 2010

This product is believed to be more potent than the ordinary benoquin ointment. Monobenzone 40% is not manufactured by any companies and is solely formulated by the pharmacies upon the physician’s request. Monobenzone 40% has the same side effects as benoquin (monobenzone 20%, see above) and must not be used by those who do not […]

Whitening Pills

Thursday, October 28th, 2010

Recently, some oral medications are claimed to induce skin depigmentation. Such medications include glutathione or arbutin containing pills. Glutathione is known to inhibit melanin synthesis in the test tube, but data confirming its efficacy as a skin whitener in human are lacking in medical journals. On the other hand, the safety of the long-term use […]

Mercury Salts

Tuesday, October 26th, 2010

Mercury salts are hazardous agents which have been used for the purpose of skin whitening for a long time. Mercury salts can be absorbed into the blood stream after topical application on the skin and may cause serious damages to several organs as kidneys. You are strongly advised to avoid any products (creams, soaps…) that […]


Monday, October 25th, 2010

Jimbow K, Quevedo WC Jr, Prota G, Fitzpatrick TB: Biology of melanocytes; in Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, Fitzpathrick TB (eds): Fitzpatrick’s Dermatology in General Medicine. New York, McGraw-Hill, 1999, pp 192-219. d’Ischia, M., A. Napolitano, et al. (1991). Peroxidase as an alternative to tyrosinase in the oxidative […]

Protected: “Traditional” Depigmenting Products – Table of Contents

Monday, August 10th, 2009

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