Posts Tagged ‘arbutine’

Melasma (Chloasma, Pregnancy Mask): Why is it so difficult to treat ?

Sunday, May 13th, 2012

One of the reasons to this therapeutical frustration is due to the lack of understanding of the pathogenesis of melasma (chloasma, pregnancy mask). Although triggering factors (ultraviolet light, pregnancy, oral contraceptives) and immunohistochemical properties of melasma are well known, molecular and genetic mechanisms which are involved a poorly understood. Scientific Consensus says the following about […]


Saturday, November 13th, 2010

Arbutin is a hydroquinone derivative found in the bearberry extract. This agent was long believed to act as a depigmenting agent. However, there are no human or even animal studies that confirm the efficacy of arbutin as a skin whitener. In addition, recent in vitro studies have cast doubt on its efficacy as a depigmenting […]

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