Section : Articles

Psoriasis and Fat around the Heart

Epicardial fat thickness is independently associated with psoriasis.
Akyildiz ZI, Seremet S, Emren V, Ozcelik S, Gediz B, Tastan A, Nazlı C.
Dermatology. 2014;228(1):55-9. doi: 10.1159/000354726. Epub 2013 Oct 18.

  • Psoriasis is associated with heart problems mainly through risk factors, altogether named “metabolic syndrome” (MS): abdominal (central) obesity, elevated blood pressure, elevated fasting plasma glucose, high serum triglycerides, and low high-density cholesterol (HDL) levels).
  • This study shows that fat (adipose tissue) around the heart (epicarial fat, EF), also appears to be associated with psoriasis.
  • Epicardial fat is known to be associated with fat in the abdominal cavity, coronary heart disease, subclinical atherosclerosis and MS.
  • In this study, echocardiography (ultrasound) was performed in 31 patients with psoriasis as well as 32 controls.
  • Results show that the thickness of the epicardial fat was higher (in a statistically significant way) in patients with psoriasis. (Statistical analysis concluded that this was independant from other cardiovascular risk factors such as MS and age)
  • Conclusion: epicardial fat tissue is associated with psoriasis as it is with cardiovascular problems.


Dr Christophe Hsu – dermatologist. Geneva, Switzerland